Pseudoephedrine (Sudafed)

NHS information about pseudoephedrine, including what it's used for, who can take it, how to take it and side effects.

What pseudoephedrine is for

Pseudoephedrine is used to treat a blocked nose caused by:

• the common cold
• flu
• allergies such as hay fever
• a sinus infection (sinusitis)

It works by reducing swelling to help mucus and air move through more easily.

Sometimes pseudoephedrine comes mixed with other medicines, such as painkillers or antihistamines. This information is about pseudoephedrine on its own.

How to take pseudoephedrine and how much to take

Pseudoephedrine comes as tablets or a liquid that you swallow.

It's usually only used for a short time at the lowest dose, until your symptoms have improved.

Always check the packet or leaflet that comes with your medicine. Ask a pharmacist or doctor for advice if you're not sure how to take it or have any problems taking it.

How to take common types of pseudoephedrine

Side effects of pseudoephedrine

Like all medicines, pseudoephedrine can cause side effects, although not everyone gets them.

Common side effects

Common side effects of pseudoephedrine include:

• feeling sick (nausea)
• headaches
• a dry mouth
• feeling nervous
• difficulty sleeping

Who can and cannot take pseudoephedrine

Most adults and children aged 6 years and over can take pseudoephedrine.

Find out more about treating colds and flu during pregnancy on the Bumps (Best Use of Medicines in Pregnancy) website

Taking pseudoephedrine with other medicines, food and drink

There are some medicines, remedies and supplements that may not mix well with pseudoephedrine.

This includes some types of:

• antidepressants, such as tricyclic antidepressants or monoamine oxidase inhibitors (MAOIs)
• medicines for heart failure, such as digoxin
• medicines for high blood pressure, such as beta blockers or methyldopa
• other cough and cold medicines – do not take pseudoephedrine with other medicines for a blocked nose, such as xylometazoline and oxymetazoline as it could make symptoms worse

This is not the full list of medicines that may not mix well with pseudoephedrine. Tell your doctor or pharmacist if you're taking any other medicines, herbal remedies, vitamins or supplements.

Food, drink and alcohol with pseudoephedrine

You can eat and drink normally (including alcohol) while taking pseudoephedrine.