Antidepressant Safety Warning Signs & Support for Your Mental Health

Antidepressants are an effective treatment for depression and, for most people, can help reduce the risk of suicide over time.

However, in some cases, particularly within the first two weeks of starting or adjusting your dosage, a small number of people may experience an increase in suicidal thoughts or behaviours.

Getting support from those around you

We encourage patients considering medication to discuss this with a trusted friend or family member so that they can help support you and help you monitor for any side effects. Having someone aware of your treatment can be reassuring and ensure you receive the help you need if any concerns arise.

Warning Signs to Watch For

If you or those around you notice any of the following symptoms, seek medical advice promptly:

  • Restlessness – Feeling unusually agitated or unable to stay still
  • Disturbing Thoughts or Urges – Thoughts that feel unlike your usual self
  • Increased Impulsiveness – Acting without thinking or taking risks you wouldn’t normally take

When to Seek Help

These symptoms can develop quickly, often within the first week of starting or increasing your medication. If you experience any of the warning signs, contact your surgery and ask for an urgent appointment. If the surgery is closed, call 111.

More information & Professional Crisis Support

The following external websites provide detailed helpful information regarding medication options. Please read them thoroughly before starting the medication so that you can ensure you have considered all the pros and cons of medication, including side effects and what to do in an emergency.

What to do in a mental health crisis

Overview of Antidepressants from the NHS Website

Young Minds - medications